603local
The Story of the 603

ARMI, BioFabUSA, and the Future of Making

How Manchester's manufacturing past connects to a federal effort to build a biofabrication industry in the millyard.

The most striking chapter of New Hampshire's modern industrial story is unfolding in the same Manchester millyard that once housed the Amoskeag mills. The Advanced Regenerative Manufacturing Institute (ARMI) is a nonprofit, Department of Defense–sponsored institute working to make large-scale manufacturing of engineered tissues and, eventually, organs practical — and to build the skilled workforce that such manufacturing would require. It is based at the Technology Center at 400 Commercial Street in Manchester.

ARMI's principal program, BioFabUSA, is a public-private partnership of more than 170 member organizations from industry, academia, government, and nonprofits, focused on developing the standards, tools, and workforce to move tissue- and cell-based innovations from the lab to commercial-scale manufacturing. It was launched as a Manufacturing USA innovation institute in July 2017, following a Department of Defense award announced in 2016 with an initial federal commitment reported at $80 million. The effort is closely associated with inventor Dean Kamen of DEKA Research & Development, whose headquarters sits in the same millyard.

The symbolism is hard to miss: a region that helped lead the textile age is now trying to help lead an age of biofabrication and advanced manufacturing. 603Local will keep this section tied to official ARMI/BioFabUSA sources and avoid overstating progress beyond what those sources support.

Sources & further reading

ARMI / BioFabUSA (official); U.S. Army

ARMI: DoD-sponsored nonprofit Manufacturing USA institute, Manchester, 400 Commercial St; BioFabUSA 170+ members, launched July 2017; initial $80M DoD grant (award announced 2016); Dean Kamen / DEKA association. Per armiusa.org, armiusa.org/biofabusa/, and army.mil/article/180090.